Prealbumin Blood Test

The prealbumin blood test, also known as the transthyretin (TTR) test, is a laboratory test used to measure the level of prealbumin in the blood.

What is Prealbumin?

Prealbumin, also known as transthyretin, is a protein produced by the liver and secreted into the blood. It plays a crucial role in transporting thyroxine (T4) and retinol-binding protein (RBP) in the blood.

Purpose of the Test

The prealbumin blood test is used to:

• Evaluate nutritional status, particularly in patients with malnutrition or those at risk of malnutrition
• Monitor the effectiveness of nutritional therapy
• Assess liver function and detect liver disease
• Diagnose and monitor certain medical conditions, such as thyroid disorders and amyloidosis

How the Test is Performed

A blood sample is collected from a vein in the arm using a needle and syringe. The sample is then sent to a laboratory for analysis.

Interpretation of Results

The normal range for prealbumin levels in the blood varies depending on the laboratory and the individual's age, sex, and nutritional status. Generally, a normal prealbumin level ranges from 15 to 35 mg/dL.

Abnormal results may indicate:

• Malnutrition or starvation
• Liver disease, such as cirrhosis or liver cancer
• Thyroid disorders, such as hypothyroidism or hyperthyroidism
• Amyloidosis, a condition characterized by the accumulation of abnormal proteins in the body

Limitations and Considerations

The prealbumin blood test has some limitations and considerations:

• Prealbumin levels can be influenced by various factors, such as inflammation, infection, and certain medications
• The test may not be suitable for patients with certain medical conditions, such as kidney disease or nephrotic syndrome
• Results should be interpreted in conjunction with other laboratory tests and clinical evaluations to ensure accurate diagnosis and treatment

Reference Range

The reference range for prealbumin levels may vary depending on the laboratory and the individual's age, sex, and nutritional status. The following are general reference ranges:

• Newborns: 10-20 mg/dL
• Infants: 15-30 mg/dL
• Children: 20-40 mg/dL
• Adults: 15-35 mg/dL
• Elderly: 10-30 mg/dL

Frequently Asked Questions (FAQs)

What is a prealbumin blood test?
Measures prealbumin levels in the blood to assess nutrition and liver function.

Why is the prealbumin blood test ordered?
To evaluate nutritional status and monitor liver disease.

What does prealbumin measure?
A protein made by the liver, also known as transthyretin.

How is the test performed?
Blood sample drawn from a vein.

Is fasting required for the test?
No, usually not required.

What are normal prealbumin levels?
15-30 mg/dL or 150-300 mg/L.

What does a low prealbumin level indicate?
Malnutrition or liver disease.

Can prealbumin levels be affected by other factors?
Yes, such as inflammation and kidney disease.

How often is the test repeated?
As needed to monitor nutritional status or liver function.

Are there any risks associated with the test?
Minimal risk of bleeding or bruising at the needle site.